Hydrochloric Acid → HCID 69963140, compound

Participants

Reaction Steps

(+,−) cis [4-(7-Hydroxy-3-phenyl-chroman-4-yl)-phenoxy]-acetic acid methyl ester (30 mg, 0.077 mmol) was stirred in 2N potassium hydroxide in methanol (1 ml) for 120 min. The reaction mixture was acidified by 1 N hydrochloric acid (2.5 ml), and stirring continued for 60 min. The precipitated product was filtered, washed with water and vacuum dried with sicapent (Merck) at 50° C. overnight.

Provenance & Evidence