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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 429760Generated: October 29, 2026

Benzyl Bromide → 4-Benzyl-2-chloro-pyrimidine

https://huagongshe.com/reaction/429760

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant2,4-DichloropyrimidineHCID 77531—
Product4-Benzyl-2-chloro-pyrimidineHCID 18353331—

Reaction Steps

The title compound (quantitiative yield) was prepared from benzyl bromide (1.71 g, 1.19 ml, 10 mmol) and 2,4-dichloropyrimidine (1.49 g, 10 mmol) in a similar manner to Intermediate 2, and was used without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06319922B1
Source datasetuspto-grants-2001_11
ORD IDord-fbe8224fb98940a19e885c83a9c33465
Source noteuspto-grants-2001_11