Hydrogen Bromide → HCID 18007940, compound

HRID 429783Notes

Reaction equation

HRID 429783 reaction equation
Br.C[O:3][C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[CH:9][CH:10]=[C:11]2[CH2:14][C:15]([OH:17])=[O:16])=[CH:6][CH:5]=1>C(O)(=O)C>[OH:3][C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[CH:9][CH:10]=[C:11]2[CH2:14][C:15]([OH:17])=[O:16])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 13570105(7-Methoxynaphthalen-1-yl)acetic acid

Product 1

HCID 18007940HCID 18007940, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In a 250 ml round-bottomed flask, dissolve 2-(7-methoxynaphth-1-yl)acetic acid in acetic acid. Add hydrobromic acid and reflux the reaction mixture for 4 hours. Remove the acetic acid and hydrobromic acid by evaporation under reduced pressure. Take up the solid in water and suction it off. Wash the precipitate with petroleum ether and recrystallise it from toluene.

Workup

  1. customRemove the acetic acid and hydrobromic acid
  2. customby evaporation under reduced pressure
  3. washWash the precipitate with petroleum ether
  4. customrecrystallise it from toluene

Sources & evidence

ORD record
ord-4f36ee42f39f4f40b6b5d98c11dd21ae
Source dataset
uspto-grants-2001_11
Patent number
US06319930B1

Reaction notes

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