HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glutaric anhydride → HCID 22335517, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glutaric anhydride | HCID 7940 | — |
| Reactant | HCID 22335511 | HCID 22335511 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22335517 | HCID 22335517 | 99% |
Reaction Steps
A mixture of 4-[1-(1H-imidazol-1-yl)-2-methylpropyl]benzenamine (0.023 mol) and dihydro-2H-pyran-2,6(3H)-dione (0.03 mol) in THF (200 ml) was stirred and refluxed for 12 hours. When the reaction was complete, the solvent was evaporated, yielding 7.5 g (±)-5-[[4-[1-(1H-imidazol-1-yl)-2-methylpropyl]phenyl]amino]-5-oxopentanoic acid (compound 218).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06319939B1 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-a839f557b6c24601abc30b08f75d4e7a |
| Source note | uspto-grants-2001_11 |