反应详情

温度

120 °C

A mixture of 34.5 g of N-(3-bromophenyl)-6-nitro-4-quinazolinamine and 16.8 g of iron powder in 150 ml of ethanol and 150 ml of glacial acetic acid was heated in an oil bath at 120° C. for 2 hours. After filtration of the solid, solid sodium carbonate was added to the filtrate giving a solid. This was filtered, and the solid was extracted with methanol. The extracts were treated with charcoal and evaporated to a solid. After washing the solid with ether 27.5 g of N-(3-bromophenyl)-4,6-quinazolindiamine was obtained: mass spectrum (m/e): 315.

1. filtrationAfter filtration of the solid, solid sodium carbonate
2. additionwas added to the filtrate
3. customgiving a solid
4. filtrationThis was filtered
5. extractionthe solid was extracted with methanol
6. additionThe extracts were treated with charcoal
7. customevaporated to a solid
8. washAfter washing the solid with ether 27.5 g of N-(3-bromophenyl)-4,6-quinazolindiamine
9. customwas obtained