HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 18351368, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 18351300 | HCID 18351300 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18351368 | HCID 18351368 | — |
Reaction Steps
7.2 g of the product obtained in Step C are added to a suspension of 2 g of LiAlH4 in 210 ml of tetrahydrofuran. After 48 hours at room temperature, the reaction mixture is hydrolysed with 1.4 ml of water, 1.1 ml of 20% sodium hydroxide solution and 5 ml of water. After filtration and concentration, chromatography over silica gel enables the expected product to be isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06323217B2 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-3a1cfbdf1aa84912af1b2d4d18f38d32 |
| Source note | uspto-grants-2001_11 |