Hydrochloric Acid → HCID 15512465, compound

HRID 430606Notes

Reaction equation

HRID 430606 reaction equation
Cl.[O:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4]([CH2:11][CH2:12][N:13]2[CH2:18][CH2:17][CH:16]([NH:19]C(=O)OC(C)(C)C)[CH2:15][CH2:14]2)=[CH:3]1>C(O)C>[O:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4]([CH2:11][CH2:12][N:13]2[CH2:14][CH2:15][CH:16]([NH2:19])[CH2:17][CH2:18]2)=[CH:3]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 69491289HCID 69491289, compound

Product 1

HCID 15512465HCID 15512465, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

235 ml of a 2.9N ethanolic hydrogen chloride solution are added to a solution of 21 g of the product obtained in Step A in 786 ml of ethanol. After 3 hours at 70° C. and then 16 hours at room temperature, the reaction mixture is concentrated under reduced pressure. The residue is taken up in 150 ml of water. The expected product is precipitated by the addition of 20% sodium hydroxide solution.

Workup

  1. concentration16 hours at room temperature, the reaction mixture is concentrated under reduced pressure
  2. customThe expected product is precipitated by the addition of 20% sodium hydroxide solution

Sources & evidence

ORD record
ord-ee95cb936fe746b78fe524f2d7d4bea3
Source dataset
uspto-grants-2001_11
Patent number
US06323217B2

Reaction notes

Loading…