HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Bromoethyl)-5-fluorobenzofuran → 4-(Aminomethyl)-1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-piperidinol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Bromoethyl)-5-fluorobenzofuran | HCID 18184296 | — |
| Reactant | ethyl N-{1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-hydroxy-4-piperidylmethyl}carbamate | HCID 70198276 | — |
| Product | 4-(Aminomethyl)-1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-piperidinol | HCID 18351356 | — |
Reaction Steps
The product is obtained according to the process of Preparation 17, using ethyl N-{1-[2-(5-fluoro-benzofuran-3-yl)ethyl]-4-hydroxy-4-piperidylmethyl}carbamate as substrate, which is prepared as for the product of Step C of Preparation 16 starting from 2-(5-fluoro-benzofuran-3-yl)-1-bromoethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06323217B2 |
| Source dataset | uspto-grants-2001_11 |
| ORD ID | ord-3fbd66f5df094705900e51ef13eaf0d3 |
| Source note | uspto-grants-2001_11 |