反应详情

温度

-5 °C

A mixture of 0.5 mmol of N-butylidenebutylamine, 1 mmol of ethyl diazoacetate, 0.025 mmol of di-p-chlorobis(1,5-cyclooctadiene)diiridium(I) [Ir2Cl2(cod)2], and 0.5 ml of tetrahydrofuran was stirred at −5° C. in an argon atmosphere for 3 hours. As a result, 1-butyl-2-ethoxycarbonyl-3-propylaziridine was obtained in a yield of 66%. Separately, small amounts of diethyl fumarate and diethyl maleate were formed as by-products in total yield of 19%.