m-Ethynylphenol → HCID 86759279, compound

HRID 431094Notes

Reaction equation

HRID 431094 reaction equation
[C:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[SH:11])(=[O:3])[CH3:2].[OH:12][C:13]1[CH:14]=[C:15]([C:19]#[CH:20])[CH:16]=[CH:17][CH:18]=1.[Na]>>[OH:12][C:13]1[CH:14]=[C:15]([CH:16]=[CH:17][CH:18]=1)/[CH:19]=[CH:20]\[C:10]1[C:5]([O:4][C:1](=[O:3])[CH3:2])=[C:6]([S:11][C:6]2[CH:7]=[CH:8][CH:9]=[C:10](/[CH:20]=[CH:19]\[C:15]3[CH:16]=[CH:17][CH:18]=[C:13]([OH:12])[CH:14]=3)[C:5]=2[O:4][C:1](=[O:3])[CH3:2])[CH:7]=[CH:8][CH:9]=1

Participants

4

Reactant 3

HCID 139144m-EthynylphenolHCID 5360545SodiumHCID 12640736HCID 12640736, compound

Product 1

HCID 86759279HCID 86759279, compoundYield 78%

Procedure

A solution of 2-acetoxythiophenol (10 mmol), 3-hydroxy-phenylacetylene (10 mmol) and sodium (0.01 g atom) was subjected to the General Procedure. The title compound was obtained in 78% yield.

Sources & evidence

ORD record
ord-167dd1e772b64424904812a6c69ba4a2
Source dataset
uspto-grants-2003_12
Patent number
US06656968B1

Reaction notes

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