m-Chloroperbenzoic acid → 2-(4-Ethylthio-3-methylpyrid-2-yl)thiazolo[3,2-a]benzimidazole-1-oxide

HRID 4311Notes

Reaction equation

HRID 4311 reaction equation
[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[S:21][C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH:11]=2)[C:5]=1[CH3:22])[CH3:2].ClC1C=C(C=CC=1)C(OO)=[O:28]>C(Cl)Cl>[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[S:21](=[O:28])[C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH:11]=2)[C:5]=1[CH3:22])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 212803642-(4-Ethylthio-3-methylpyrid-2-yl)-thiazolo[3,2-a]benzimidazole

Product 1

HCID 212803682-(4-Ethylthio-3-methylpyrid-2-yl)thiazolo[3,2-a]benzimidazole-1-oxide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 2-(4-ethylthio-3-methylpyrid-2-yl)-thiazolo[3,2-a]benzimidazole (0.01 mole) is dissolved in CH2Cl2 solution (100 ml) at 0° C. and treated with m-chloroperoxybenzoic acid (0.01 mole) for 0.5 hours. The solution is then washed with sodium carbonate solution and dried (MgSO4). Purification by chromatography on silica gives the title compound.

Workup

  1. washThe solution is then washed with sodium carbonate solution
  2. dry with materialdried (MgSO4)
  3. customPurification by chromatography on silica

Sources & evidence

ORD record
ord-a0df9816cf51486da9d534d6342d0836
Source dataset
uspto-grants-1988_02
Patent number
US04725605

Reaction notes

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