HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-chloro-4-ethynyl- → Z-4-chlorostyryl 4-fluorobenzylsulfide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-chloro-4-ethynyl- | HCID 70118 | — |
| Reactant | p-Fluorotoluene-alpha-thiol | HCID 85171 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Product | Z-4-chlorostyryl 4-fluorobenzylsulfide | HCID 86588939 | — |
Reaction Steps
A solution of 4-chlorophenylacetylene (0.02 mol) and 4-fluorobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) was subjected to Procedure 2 to form (Z)-4-chlorostyryl 4-fluorobenzylsulfide. The title compound was obtained in 82% yield following oxidation. 1HNMR (CDC13) δ4.60 (2H, s), 6.70 (1H, d, JH,H=11.78), 7.18-7.60 (8H aromatic+1H ethylenic).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06656973B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-90d892b33062452e909d265679bd20d0 |
| Source note | uspto-grants-2003_12 |