HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Fluorotoluene-alpha-thiol → Z-4-fluorostyryl 4-fluorobenzylsulfide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Fluorotoluene-alpha-thiol | HCID 85171 | — |
| Reactant | 1-Ethynyl-4-fluorobenzene | HCID 522627 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Product | Z-4-fluorostyryl 4-fluorobenzylsulfide | HCID 86588943 | — |
Reaction Steps
A solution of 4-fluorophenylacetylene (0.02 mol) and 4-fluorobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) was subjected to Procedure 2 to form (Z)-4-fluorostyryl 4-fluorobenzylsulfide. The title compound was obtained in 78% yield following oxidation. 1HNMR (CDC13) δ4.60 (2H, s), 6.65 (1H, d, JH,H=11.83), 7.20-7.65 (8H aromatic+1H ethylenic).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06656973B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-07eec70903ad40c7b5cb75c7b04bf834 |
| Source note | uspto-grants-2003_12 |