Acetaldehyde → HCID 22335574, compound

HRID 431199Notes

Reaction equation

HRID 431199 reaction equation
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([OH:10])=[O:9])[N:6]=1.[CH:11]1([N+:17]#[C-:18])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1.[CH:19](=O)[CH3:20]>Cl(O)(=O)(=O)=O>[CH:11]1([NH:17][C:18]2[N:6]3[C:2]([S:3][CH:4]=[C:5]3[CH2:7][C:8]([OH:10])=[O:9])=[N:1][C:19]=2[CH3:20])[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

5

Reactant 3

HCID 177AcetaldehydeHCID 34665(2-Amino-1,3-thiazol-4-yl)acetic acidHCID 79129Cyclohexyl isocyanide

Product 1

HCID 22335574HCID 22335574, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound 17 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) (2-aminothiazol-4-yl)acetic acid solution (0.1 M, MC), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) acetaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

Sources & evidence

ORD record
ord-a1034d00129b48c88f54ae981db53f4f
Source dataset
uspto-grants-2003_12
Patent number
US06657064B2

Reaction notes

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