2-Methylbenzaldehyde → HCID 22335568, compound

HRID 431215Notes

Reaction equation

HRID 431215 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[C:7]([N+:11]#[C-:12])([CH3:10])([CH3:9])[CH3:8].[CH3:13][C:14]1[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=1[CH:16]=O>Cl(O)(=O)(=O)=O>[C:7]([NH:11][C:12]1[N:3]2[NH:4][CH:5]=[N:6][C:2]2=[N:1][C:13]=1[C:14]1[CH:21]=[CH:20][CH:19]=[CH:18][C:15]=1[CH3:16])([CH3:10])([CH3:9])[CH3:8]

Participants

5

Reactant 3

HCID 107222-MethylbenzaldehydeHCID 23577Tert-Butyl isocyanideHCID 178418311HCID 178418311, compound

Product 1

HCID 22335568HCID 22335568, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound 34 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) tert-butylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2-methylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

Sources & evidence

ORD record
ord-1581f7efe0c8467c80c3b28234f2a295
Source dataset
uspto-grants-2003_12
Patent number
US06657064B2

Reaction notes

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