1,1,3,3-Tetramethylbutyl isocyanide → HCID 22335550, compound

HRID 431226Notes

Reaction equation

HRID 431226 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH3:7][C:8]([N+:15]#[C-:16])([CH3:14])[CH2:9][C:10]([CH3:13])([CH3:12])[CH3:11].[Br:17][C:18]1[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=1[CH:20]=O>Cl(O)(=O)(=O)=O>[Br:17][C:18]1[CH:25]=[CH:24][CH:23]=[CH:22][C:19]=1[C:20]1[N:1]=[C:2]2[N:6]=[CH:5][NH:4][N:3]2[C:16]=1[NH:15][C:8]([CH3:14])([CH3:7])[CH2:9][C:10]([CH3:13])([CH3:12])[CH3:11]

Participants

5

Reactant 3

HCID 267251,1,3,3-Tetramethylbutyl isocyanideHCID 811292-BromobenzaldehydeHCID 178418311HCID 178418311, compound

Product 1

HCID 22335550HCID 22335550, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound 47 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 1,1,3,3-tetramethylbutylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 2-bromobenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

Sources & evidence

ORD record
ord-9fed47d7e3e0489f85b5e136e56988f6
Source dataset
uspto-grants-2003_12
Patent number
US06657064B2

Reaction notes

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