4-Acetamidobenzaldehyde → HCID 69158331, compound

HRID 431227Notes

Reaction equation

HRID 431227 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH:7]1([N+:13]#[C-:14])[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1.[CH:15]([C:17]1[CH:22]=[CH:21][C:20]([NH:23][C:24](=[O:26])[CH3:25])=[CH:19][CH:18]=1)=O>Cl(O)(=O)(=O)=O>[CH:7]1([NH:13][C:14]2[N:3]3[NH:4][CH:5]=[N:6][C:2]3=[N:1][C:15]=2[C:17]2[CH:18]=[CH:19][C:20]([NH:23][C:24](=[O:26])[CH3:25])=[CH:21][CH:22]=2)[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1

Participants

5

Reactant 3

HCID 739424-AcetamidobenzaldehydeHCID 79129Cyclohexyl isocyanideHCID 178418311HCID 178418311, compound

Product 1

HCID 69158331HCID 69158331, compound

Reagents, catalysts & solvents 1

HCID 24247Perchloric AcidSolvent

Procedure

Compound 48 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 3-amino-1,2,4-triazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) N-(4-formyl-phenyl)-acetamide solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

Sources & evidence

ORD record
ord-68eb0d0610e04962a70fdca74527ae4b
Source dataset
uspto-grants-2003_12
Patent number
US06657064B2

Reaction notes

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