1,3-Dioxolane-4-methanol, 2-ethyl-2-methyl- → HCID 18763754, compound

HRID 431305Notes

Reaction equation

HRID 431305 reaction equation
[CH3:1][C:2]1([CH2:9][CH3:10])[O:6][CH:5]([CH2:7][OH:8])[CH2:4][O:3]1>[Pd]>[CH:2]([O:3][CH2:4][CH:5]([OH:6])[CH2:7][OH:8])([CH2:9][CH3:10])[CH3:1]

Participants

3

Reactant 1

HCID 118049031,3-Dioxolane-4-methanol, 2-ethyl-2-methyl-

Product 1

HCID 18763754HCID 18763754, compoundYield 183.5%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The compound obtained in the production (1) (29.2 g, 0.10 mol) and the palladium catalyst (2) (2.2 g) were charged in a 70-mL autoclave, followed by a reaction under a hydrogen pressure of 7.0MPa at 190° C. for 15 hours. After completion of the reaction, the catalyst was removed by filtration to obtain a crude product (27.2 g).

Workup

  1. customfollowed by a reaction under a hydrogen pressure of 7.0MPa at 190° C. for 15 hours
  2. customAfter completion of the reaction
  3. customthe catalyst was removed by filtration

Sources & evidence

ORD record
ord-1a24222e394e4fd5aa78c72958a4dcd2
Source dataset
uspto-grants-2003_12
Patent number
US06657089B1

Reaction notes

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