3,5-Dichlorophenyl isothiocyanate → HCID 86586379, compound

HRID 431380Notes

Reaction equation

HRID 431380 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([N:19]([C:22]2[CH:27]=[C:26]([Cl:28])[CH:25]=[C:24]([Cl:29])[CH:23]=2)[CH:20]=[O:21])[CH:5]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=2)[CH:7]=1.[Cl:30][C:31]1[CH:32]=[C:33]([N:38]=[C:39]=[S:40])[CH:34]=[C:35]([Cl:37])[CH:36]=1>CC(N(C)C)=O>[Cl:29][C:24]1[CH:23]=[C:22]([N:19]([C:4]2[CH:3]=[C:2]([NH:1][C:39]([NH:38][C:33]3[CH:34]=[C:35]([Cl:37])[CH:36]=[C:31]([Cl:30])[CH:32]=3)=[S:40])[CH:7]=[C:6]([NH:8][C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:17])([F:18])[F:16])[CH:10]=3)[CH:5]=2)[CH:20]=[O:21])[CH:27]=[C:26]([Cl:28])[CH:25]=1

Participants

4

Reactant 2

HCID 1387763,5-Dichlorophenyl isothiocyanateHCID 86586377HCID 86586377, compound

Product 1

HCID 86586379HCID 86586379, compound

Reagents, catalysts & solvents 1

HCID 31374DimethylacetamideSolvent

Procedure

To a solution of N-(3-amino-5-{[3-(trifluoromethyl)phenyl]amino}phenyl)(3,5-dichloro-phenyl)formamide (0.54 g, 1.2 mmol), in DMA (10 mL) was added 3,5-dichlorophenylisothiocyanate (0.30 g, 1.5 mmol) and the mixture stirred overnight.

Sources & evidence

ORD record
ord-0b6af63b02e14c88a23811b61f14b315
Source dataset
uspto-grants-2003_12
Patent number
US06656971B2

Reaction notes

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