Trimethylamine → HCID 86585517, compound

HRID 431419Notes

Reaction equation

HRID 431419 reaction equation
[Cl:1][C:2]([C:4]12[CH2:13][C:8]3([OH:14])[CH2:9][CH:10]([CH2:12][C:6]([C:15]([Cl:17])=[O:16])([CH2:7]3)[CH2:5]1)[CH2:11]2)=[O:3].CN(C)C.[CH3:22][Si:23](Cl)([CH3:25])[CH3:24]>C(Cl)Cl>[Cl:1][C:2]([C:4]12[CH2:13][C:8]3([O:14][Si:23]([CH3:25])([CH3:24])[CH3:22])[CH2:9][CH:10]([CH2:12][C:6]([C:15]([Cl:17])=[O:16])([CH2:7]3)[CH2:5]1)[CH2:11]2)=[O:3]

Participants

5

Reactant 3

HCID 1146TrimethylamineHCID 6397ChlorotrimethylsilaneHCID 21930705HCID 21930705, compound

Product 1

HCID 86585517HCID 86585517, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The 1,3-dichloroformyl-5-hydroxyadamantane was dissolved in methylene chloride. To this solution were added a small amount of trimethylamine, and then an equimolar amount of trimethylsilyl chloride. Reaction was carried out at room temperature to obtain 1,3-dichloroformyl-5-trimethylsiloxyadamantane.

Workup

  1. customReaction
  2. customwas carried out at room temperature

Sources & evidence

ORD record
ord-0bf4edad633e4a898e3af4f4cb85a9d6
Source dataset
uspto-grants-2003_12
Patent number
US06660450B2

Reaction notes

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