2-Pyridinecarboxaldehyde → HCID 6849020, compound

HRID 431498Notes

Reaction equation

HRID 431498 reaction equation
[NH:1]1[C:13]2[NH:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[N:4]=[N:3][C:2]1=[N:14][NH2:15].[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[CH:22]=O>C(O)C>[N:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[CH:22]=[N:15][NH:14][C:2]1[N:3]=[N:4][C:5]2[C:6]3[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=3)[NH:12][C:13]=2[N:1]=1

Participants

4

Reactant 2

HCID 142732-PyridinecarboxaldehydeHCID 178514365HCID 178514365, compound

Product 1

HCID 6849020HCID 6849020, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
60 °C

Procedure

To a solution of (1,9-Dihydro-1,3,4,9-tetraaza-fluoren-2-ylidene)-hydrazine 14d (27 mmol, 1 equiv.) in ethanol (50 mL) is added 2-pyridinecarboxaldehyde (27 mmol, 1 equiv.). The mixture is heated at 60° C. for 10 hours. The solution is allowed to cool to room temperature. The product is filtered and dried under vacuum for 15 hours. N-Pyridin-2-ylmethylene-N′-(9H-1,3,4,9-tetraaza-fluoren-2-yl)-hydrazine 14e is obtained as a pale yellow solid.

Workup

  1. temperatureto cool to room temperature
  2. filtrationThe product is filtered
  3. customdried under vacuum for 15 hours

Sources & evidence

ORD record
ord-8eff193429cb452b94562452bed9862f
Source dataset
uspto-grants-2003_12
Patent number
US06660737B2

Reaction notes

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