HCID 54549583, compound → HCID 10107954, compound

HRID 431506Notes

Reaction equation

HRID 431506 reaction equation
[C:1]([O:5][C:6]([C:8]1[S:9][C:10]([CH:13]=[CH:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:11][CH:12]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[H][H]>C(O)C.[Pd]>[C:1]([O:5][C:6]([C:8]1[S:9][C:10]([CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:11][CH:12]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 2

HCID 54549583HCID 54549583, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 10107954HCID 10107954, compoundYield 70.3%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

0.846 g (3 mmol) of the product obtained in step d) were dissolved in 100 ml of dry ethanol. 150 mg of 10% palladium on charcoal were added, and the suspension was hydrogenated at 50° C. and 4 bar hydrogen pressure. After filtration the solvent was removed in vacuo. 0.6 g of a colourless oil were obtained.

Workup

  1. customwas hydrogenated at 50° C.
  2. filtrationAfter filtration the solvent
  3. customwas removed in vacuo

Sources & evidence

ORD record
ord-074d49f404c746369c7bdb1fda0e1ba2
Source dataset
uspto-grants-2003_12
Patent number
US06660728B2

Reaction notes

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