反应详情

48 mg of the product obtained in step c) were dissolved in 2 ml of dichloromethane and stirred for 3 hours with 1 ml of trifluoroacetic acid under an inert gas atmosphere at room temperature. The solvents were removed in vacuo, the residue was dissolved in acetic acid and the solution was again evaporated to dryness. This procedure was repeated once. The resinous residue was triturated with diethyl ether. After filtration 30 mg of the title compound were obtained as a colourless amorphous powder.

1. customThe solvents were removed in vacuo
2. dissolutionthe residue was dissolved in acetic acid
3. customthe solution was again evaporated to dryness
4. customThe resinous residue was triturated with diethyl ether
5. filtrationAfter filtration 30 mg of the title compound
6. customwere obtained as a colourless amorphous powder