反应详情

To a solution of benzyl (2R, 4R)-2-(4,5-diphenyloxazol-2-yl)-4-hydroxypyrrolidine-1-carboxylate (350 mg) in MeOH (15 mL) was added 10%Pd-C (wet) (50 mg), and the mixture was stirred under hydrogen atmosphere at room temperature for 1 hour. The catalyst was removed by filtration and the filtrate was evaporated to give (2R, 4R)-2-(4,5-diphenyloxazol-2-yl)pyrrolidin-4-ol (236.8 mg).

1. customThe catalyst was removed by filtration
2. customthe filtrate was evaporated