3-Nitrophenol → HCID 18760029, compound

HRID 432633Notes

Reaction equation

HRID 432633 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12](Cl)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1.[N+:24]([C:27]1[CH:28]=[C:29]([OH:33])[CH:30]=[CH:31][CH:32]=1)([O-:26])=[O:25]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12]([O:33][C:29]3[CH:30]=[CH:31][CH:32]=[C:27]([N+:24]([O-:26])=[O:25])[CH:28]=3)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 111373-NitrophenolHCID 125680843,4-Bis(4-methoxyphenyl)-6-chloropyridazine

Product 1

HCID 18760029HCID 18760029, compound

Procedure

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (106.9 mg, 0.327 mmol) and 3-nitrophenol were reacted as starting materials at 150° C. for 17 hours and post-treatment was then conducted, whereby the title compound was obtained as pale yellow prisms (140.4 mg, 99.9%). Melting point: 172.2-174.0° C. (ethyl acetate-diethyl ether-hexane).

Workup

  1. customat 150° C.
  2. customfor 17 hours

Sources & evidence

ORD record
ord-d52c822527924265b9eb4ce6d8550d55
Source dataset
uspto-grants-2003_12
Patent number
US06664256B1

Reaction notes

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