2,4-Difluorophenol → HCID 18760000, compound

Participants

Reaction Steps

In a similar manner as in Example 2, 6-chloro-4-(4-fluorophenyl)-3-[4-(methylthio)phenyl]pyridazine (198 mg, 0.599 mmol) and 2,4-difluorophenol were reacted as starting materials at 150° C. for 20 hours and post-treatment was then conducted, whereby the title compound was obtained as pale yellow crystals (197 mg, 77.4%). Melting point: 140.6-143.4° C. (acetone-water).

Provenance & Evidence