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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 432647Generated: October 31, 2026

2,4-Difluorophenol → HCID 10297058, compound

https://huagongshe.com/reaction/432647

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorophenolHCID 123051—
ReactantHCID 18760020HCID 18760020—
SolventMethylenechloride HexaneHCID 21226440—
ProductHCID 10297058HCID 10297058—

Reaction Steps

In a similar manner as in Example 2, 6-chloro-4-(4-chlorophenyl)-3-[4-(methylthio)phenyl]pyridazine (230.0 mg, 0.662 mmol) and 2,4-difluorophenol were reacted as starting materials at 150° C. for 20 hours and post-treatment was then conducted, whereby the title compound was obtained as colorless plates (dichloromethane-hexane, 216.2 mg, 74.0%). Melting point: 163.2-164.0° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06664256B1
Source datasetuspto-grants-2003_12
ORD IDord-84f2adfd236f4e7682dc212d947aea6f
Source noteuspto-grants-2003_12