Benzylamine → HCID 18760036, compound

HRID 432651Notes

Reaction equation

HRID 432651 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12](Cl)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1.[CH2:24]([NH2:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:24]([NH:31][C:12]1[N:11]=[N:10][C:9]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[C:14]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)[CH:13]=1)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 125680843,4-Bis(4-methoxyphenyl)-6-chloropyridazine

Product 1

HCID 18760036HCID 18760036, compound

Procedure

In a similar manner as in Example 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (300 mg, 0.918 mmol) and benzylamine were reacted as starting materials at 120° C. for 19 hours and post-treatment was then conducted, whereby the title compound was obtained as colorless prisms (365 mg, quantitative). Melting point: 125.4-126.3° C. (ethyl acetate-hexane).

Workup

  1. customat 120° C.
  2. customfor 19 hours

Sources & evidence

ORD record
ord-2cdb8ca9b2a7439e847d9b33a328e7dc
Source dataset
uspto-grants-2003_12
Patent number
US06664256B1

Reaction notes

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