Chloroform → HCID 18760543, compound

HRID 432896Notes

Reaction equation

HRID 432896 reaction equation
[CH2:1]([C:3]([NH2:11])([CH3:10])[CH2:4][NH:5][C:6]([CH3:9])([CH3:8])[CH3:7])[CH3:2].[CH2:12]([C:14]([CH2:16][CH3:17])=O)[CH3:13].[OH-:18].[Na+].[CH:20](Cl)(Cl)Cl>>[C:6]([N:5]1[CH2:4][C:3]([CH2:1][CH3:2])([CH3:10])[NH:11][C:14]([CH2:16][CH3:17])([CH2:12][CH3:13])[C:20]1=[O:18])([CH3:9])([CH3:8])[CH3:7]

Participants

5

Reactant 4

HCID 6212ChloroformHCID 7288Ethyl ketoneHCID 14798Sodium HydroxideHCID 18760475HCID 18760475, compound

Product 1

HCID 18760543HCID 18760543, compoundYield 71%

Procedure

In analogy to Example B21, 1-ethyl-1-methyl-2-t-butylaminoethylamin, diethylketon, chloroform and NaOH are reacted to give the raw title compound (71%) as an yellow oil.

Sources & evidence

ORD record
ord-810cf098a176430aa41c4c934e16c1b1
Source dataset
uspto-grants-2003_12
Patent number
US06664353B2

Reaction notes

Loading…