(R)-(-)-1-Methyheptyl 4-Methoxycarbonyloxybenzoate → (R)-(-)-1-Methylheptyl 4-Hydroxybenzoate

HRID 433043Notes

Reaction equation

HRID 433043 reaction equation
COC([O:5][C:6]1[CH:22]=[CH:21][C:9]([C:10]([O:12][C@H:13]([CH3:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[O:11])=[CH:8][CH:7]=1)=O>C(O)C.N>[OH:5][C:6]1[CH:22]=[CH:21][C:9]([C:10]([O:12][C@H:13]([CH3:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[O:11])=[CH:8][CH:7]=1

Participants

4

Reactant 1

HCID 70010659(R)-(-)-1-Methyheptyl 4-Methoxycarbonyloxybenzoate

Product 1

HCID 13980124(R)-(-)-1-Methylheptyl 4-Hydroxybenzoate

Reagents, catalysts & solvents 2

HCID 222AmmoniaSolventHCID 702EthanolSolvent

Procedure

Compound 3 (11.6 g, 38 mmol) in ethanol (200 ml) and aqueous ammonia (50 ml) was stirred overnight. The solvents were removed in vacuo and the resulting colourless oil was purified by column chromatography (ethyl acetate) on silica.

Workup

  1. customThe solvents were removed in vacuo
  2. customthe resulting colourless oil was purified by column chromatography (ethyl acetate) on silica

Sources & evidence

ORD record
ord-b0f16c51de7747f9ab721b7f67c9b915
Source dataset
uspto-grants-2003_12
Patent number
US06666989B1

Reaction notes

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