Ethyl tiglate → HCID 56949563, compound

HRID 43307Notes

Reaction equation

HRID 43307 reaction equation
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])/[C:2](=[CH:4]/[CH3:5])/[CH3:3].[C:10]([OH:13])(=[S:12])[CH3:11]>>[C:10]([S:12][CH:4]([CH3:5])[CH:2]([CH3:3])[C:1]([O:7][CH2:8][CH3:9])=[O:6])(=[O:13])[CH3:11]

Participants

3

Reactant 2

HCID 5281163Ethyl tiglate2×HCID 178418634HCID 178418634, compound

Product 1

HCID 56949563HCID 56949563, compound

Procedure

A mixture of 3.20 g (0.025 mol) of ethyl tiglate and 4.76 g (0.0625 mol) of thioacetic acid was prepared and allowed to react under nitrogen atmosphere at 85° C. for 24 hours. The results showed that the conversion rate of ethyl tiglate was 35.3%, and that the selectivity for the objective compound was 91.6%.

Workup

  1. customwas prepared
  2. customto react under nitrogen atmosphere at 85° C. for 24 hours

Sources & evidence

ORD record
ord-9a99f6c83ecb45f2a14080de6416e4b9
Source dataset
uspto-grants-2013_09
Patent number
US08536364B2

Reaction notes

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