HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-((S)-2-(4,4-Dimethyl-3-(4-styrylbenzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-methylpropionic Acid → (r)-3-((s)-2-(4,4-Dimethyl-3-(4-(2-phenylethyl)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-methylpropionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-((S)-2-(4,4-Dimethyl-3-(4-styrylbenzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-methylpropionic Acid | HCID 68420215 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (r)-3-((s)-2-(4,4-Dimethyl-3-(4-(2-phenylethyl)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-methylpropionic acid | HCID 9828091 | — |
Reaction Steps
The compound was prepared by catalytic hydrogenation of the styryl compound obtained in Example 1 (Pd/C, 1 bar hydrogen overpressure, methanol, room temperature).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06667334B1 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-f4c89a5c73cd4d568b801a968751f277 |
| Source note | uspto-grants-2003_12 |