HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 131724045, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4,5,6,7-Tetrahydro-1H-benzimidazole | HCID 304263 | — |
| Reactant | 4-Chloromethyl-1-(3,4-dichloro-phenyl)-1H-imidazole | HCID 23445032 | — |
| Product | HCID 131724045 | HCID 131724045 | — |
Reaction Steps
Reaction of 4,5,6,7-tetrahydrobenzimidazole with sodium hydride followed by treatment with 4-chloromethyl-1-(3,4-dichloro-phenyl)-1H-imidazole led after extractive workup and chromatography to the free base of the title compound which was converted into its white hydrochloride salt. Mp. >250° C. (MeOH/Et2O), MS: m/e=346 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06667335B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-05a4da84369548b2bb4f1c78263eb8ea |
| Source note | uspto-grants-2003_12 |