HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Trifluoromethyl)trimethylsilane → HCID 22645731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Trifluoromethyl)trimethylsilane | HCID 552549 | — |
| Reactant | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| Reactant | HCID 9899948 | HCID 9899948 | — |
| Reactant | HCID 178418573 | HCID 178418573 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22645731 | HCID 22645731 | — |
Reaction Steps
If 5-chloro-2-fluoro-2-methanesulfonylindan-1-one is, instead of methylmagnesium bromide, reacted with trifluoromethyltrimethylsilane and tetrabutylammonium fluoride in tetrahydrofuran, 5-chloro-2-fluoro-2-methyanesulfonyl-1-trifluoromethylindan-1-ol of molecular weight 332.7 (C11H9CIF4SO3); MS (ESI): 333.20 (MH+) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06670401B2 |
| Source dataset | uspto-grants-2003_12 |
| ORD ID | ord-bf5b56e6ce6c47a1b43f66cdb3f80ed4 |
| Source note | uspto-grants-2003_12 |