Diethylamine → Ethyl 3-(diethylamino)acrylate

HRID 434325노트

반응식

HRID 434325 반응식
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].[C:6]([O:10][CH2:11][CH3:12])(=[O:9])[C:7]#[CH:8]>C(O)C>[CH2:1]([N:3]([CH2:4][CH3:5])[CH:8]=[CH:7][C:6]([O:10][CH2:11][CH3:12])=[O:9])[CH3:2]

참가 물질

4

반응물 2

HCID 8021DiethylamineHCID 12182Ethyl propiolate

생성물 1

HCID 139639Ethyl 3-(diethylamino)acrylate수율 87.3%

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

A solution of 14.6 g of diethylamine (0.2 m) in 100 ml of ethyl alcohol was added dropwise to a stirred solution of 19.6 g of ethyl propiolate (0.2 m) in 150 ml ethyl alcohol at room temperature. The exothermic reaction mixture was stirred at room temperature for 31/2 hours. The solvent was removed and the residue distilled through a short Vigreux column (boiling point 88° C./6 mm) to give 29.83 g (87 percent) of ethyl 3-(diethylamino)acrylate.

후처리

  1. customThe solvent was removed
  2. distillationthe residue distilled through a short Vigreux column (boiling point 88° C./6 mm)

출처 및 근거

ORD 기록
ord-f9f73dfc1b934ca49d3924242c09a748
출처 데이터셋
uspto-grants-1983_08
특허 번호
US04396546

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