反应详情

温度

120 °C

Ethylamine (115 grams; 1.77 mole) and 2-methyl-2-bromomethyl-1,3-dioxolane (32 grams; 0.177 mole) were placed in a stainless steel bomb and placed on a steam bath for 5 hours. The temperature of the mixture was raised to 120° C. for 15 hours. The mixture was cooled and ether (200 ml) added to it. Sodium hydroxide (25 grams) was added and the ether layer separated and dried over magnesium sulfate. The ether was evaporated leaving the desired product (10.3 grams) as identified by nuclear magnetic resonance.

1. temperatureThe mixture was cooled
2. customthe ether layer separated
3. dry with materialdried over magnesium sulfate
4. customThe ether was evaporated