Sodium Hydroxide → HCID 13189003, compound

Participants

Reaction Steps

To a stirred solution of 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxy-1-piperidinyl)-4-oxoquinoline-3-carboxylic acid (235 mg), sodium hydroxide (26.7 mg), and water (3 ml), a solution of silver nitrate (113 mg) and water (2 ml) was added. The precipitate was filtered off, washed with water, and dried to give 1-ethyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxy-1-piperidinyl)-4-oxoquinoline-3-carboxylic acid silver salt (284 mg), mp 181°-184° C. (decomp.).

Provenance & Evidence