HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-methylbutan-2-one → 2-(3-Methyl-2-oxobutyl)-1h-isoindole-1,3(2h)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-methylbutan-2-one | HCID 10899037 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Product | 2-(3-Methyl-2-oxobutyl)-1h-isoindole-1,3(2h)-dione | HCID 277811 | 74.1% |
Reaction Steps
The same operation as in Example (15b) was performed using 1-bromo-3-methylbutan-2-one obtained in Example (35a) (3.94 g, 23.9 mmol) and potassium phthalimide (4.4 g, 23.8 mmol), to obtain 4.08 g of the title compound as a white solid (74%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536197B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-d78db5d42f044ec790793357f13b9257 |
| Source note | uspto-grants-2013_09 |