Tetrahydrofuran → HCID 13092031, compound

HRID 434833Notes

Reaction equation

HRID 434833 reaction equation
Cl.[Cl:2][C:3]1[C:4]([CH3:16])=[C:5]([CH:11]([OH:15])[C:12](=[NH:14])[OH:13])[C:6]([O:9][CH3:10])=[CH:7][CH:8]=1.[O:17]1CCC[CH2:18]1>C1(C)C=CC=CC=1>[Cl:2][C:3]1[C:4]([CH3:16])=[C:5]([CH:11]2[O:15][C:18](=[O:17])[NH:14][C:12]2=[O:13])[C:6]([O:9][CH3:10])=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 8028TetrahydrofuranHCID 178490729HCID 178490729, compound

Product 1

HCID 13092031HCID 13092031, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

By the procedure of Example 27, 1-(3-chloro-6-methoxy-2-methylphenyl)-1-hydroxymethanecarboximidate hydrochloride (1.0 g., 3.4 mmoles) in 50 ml. of tetrahydrofuran was converted to toluene recrystallized 5-(3-chloro-6-methoxy-2-methylphenyl)oxazolidine-2,4-dione (470 mg. 54%; m.p. 193°-195° C.).

Workup

  1. customrecrystallized 5-(3-chloro-6-methoxy-2-methylphenyl)oxazolidine-2,4-dione (470 mg. 54%; m.p. 193°-195° C.)

Sources & evidence

ORD record
ord-cb92cc9ef1154fb6b28a36f97a462113
Source dataset
uspto-grants-1983_08
Patent number
US04399296

Reaction notes

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