Benzene → HCID 12962346, compound

HRID 435057Notes

Reaction equation

HRID 435057 reaction equation
C1C=CC=CC=1.[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([CH:14]2[NH:18][CH2:17][CH2:16][O:15]2)=[CH:10][CH:9]=1.[Cl:19][CH:20]([Cl:24])[C:21](Cl)=[O:22]>C(N(CC)CC)C>[Cl:7][C:8]1[CH:9]=[CH:10][C:11]([CH:14]2[N:18]([C:21](=[O:22])[CH:20]([Cl:24])[Cl:19])[CH2:17][CH2:16][O:15]2)=[CH:12][CH:13]=1

Participants

5

Reactant 3

HCID 241Benzene2×HCID 6593Dichloroacetyl chlorideHCID 10058192Oxazolidine, 2-(4-chlorophenyl)-

Product 1

HCID 12962346HCID 12962346, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

Twenty-two (22) ml. of a benzene solution containing 5.5 g. of 2-p-chlorophenyl oxazolidine was mixed with 25 ml. of benzene and 3.1 g. of triethylamine and stirred at room temperature, while 4.4 g. of dichloroacetyl chloride was added dropwise. The mixture was allowed to stand for about 30 minutes, washed with water, separated, dried over magnesium sulfate and then stripped. There was obtained a yield of 8.4 g. of an oil, the title compound, ND30 =1.5668.

Workup

  1. washwashed with water
  2. customseparated
  3. dry with materialdried over magnesium sulfate
  4. customThere was obtained a yield of 8.4 g

Sources & evidence

ORD record
ord-9c56027331a74437b663051b41bb47d0
Source dataset
uspto-grants-1983_08
Patent number
US04400200

Reaction notes

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