HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → 1,3-dimethyl-8-(morpholin-4-yl)-3,7-dihydro-1H-purine-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Bromotheophylline | HCID 11808 | — |
| Product | 1,3-dimethyl-8-(morpholin-4-yl)-3,7-dihydro-1H-purine-2,6-dione | HCID 766772 | 80% |
Reaction Steps
0.3 moles of the 8-bromo-theophylline, prepared as in the previous paragraph, is refluxed in 1.5 moles of morpholine for two hours. The precipitate obtained is filtered, to give approximately 80% yield of 8-morpholino-theophylline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04400381 |
| Source dataset | uspto-grants-1983_08 |
| ORD ID | ord-122ed7faa1f54c038032af7d70cad165 |
| Source note | uspto-grants-1983_08 |