HRID435324

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

结构：O=CNc1nc(C(=NOC2CCCCC2)C(=O)NC2C(=O)N3C(C(=O)O)=CCS[C@H]23)cs1

HCID131712463

未命名化合物

PRODUCTS

生成物

结构：Nc1nc(C(=NOC2CCCCC2)C(=O)NC2C(=O)N3C(C(=O)O)=CCS[C@H]23)cs1

HCID131712464

未命名化合物

收率 41.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

7-[2-(2-Formamidothiazol-4-yl)-2-cyclohexyloxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 0.72 g.), methanol (10.8 ml.) and conc. hydrochloric acid (0.61 g.) were treated in a similar manner to that of Example 15-(3) to give 7-[2-(2-aminothiazol-4-yl)-2-cyclohexyloxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 0.28 g.).