2-Pyridinecarboxaldehyde → HCID 70638589, compound

HRID 435571Notes

Reaction equation

HRID 435571 reaction equation
[I-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH3:8])[CH:4]1[CH3:9].[N:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH:16]=O>[OH-].[K+].C(O)C>[I-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH3:8])[CH:4]1[CH:9]=[CH:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][N:10]=1

Participants

5

Reactant 2

HCID 142732-PyridinecarboxaldehydeHCID 70639049HCID 70639049, compound

Product 1

HCID 70638589HCID 70638589, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14797Potassium HydroxideSolvent

Procedure

A mixture of 12.0 g of 1,2,3-trimethyl-1H-imidazolium iodide and 12 ml of 2-pyridinecarboxaldehyde in 40 ml of 10% potassium hydroxide in absolute ethanol is refluxed for 15 minutes. The resulting solid is filtered off and crystallized from absolute ethanol to yield 3.5 g of the title compound, melting point 306° C.

Workup

  1. temperatureis refluxed for 15 minutes
  2. filtrationThe resulting solid is filtered off
  3. customcrystallized from absolute ethanol

Sources & evidence

ORD record
ord-f1f61f36edeb49eabc80650a90624223
Source dataset
uspto-grants-1977_02
Patent number
US04006137

Reaction notes

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