Water → HCID 70638261, compound

HRID 435572Notes

Reaction equation

HRID 435572 reaction equation
[I-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH3:8])[CH:4]1[CH3:9].[OH-].[K+].[CH3:12][N:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[CH:18]=O.O>C(O)C>[I-:1].[CH3:2][NH+:3]1[CH:7]=[CH:6][N:5]([CH3:8])[CH:4]1[CH:9]=[CH:18][C:14]1[N:13]([CH3:12])[CH:17]=[CH:16][CH:15]=1

Participants

6

Reactant 4

HCID 962WaterHCID 145041-Methyl-1H-pyrrole-2-carbaldehydeHCID 14797Potassium HydroxideHCID 70639049HCID 70639049, compound

Product 1

HCID 70638261HCID 70638261, compoundYield 74.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 12.0 g of 1,2,3-trimethyl-1H-imidazolium iodide, 2g of potassium hydroxide and 12.0 g of N-methylpyrrole-2-carboxaldehyde in 60 ml of absolute ethanol is refluxed for 15 minutes during which time a precipitate is formed. The mixture is cooled and 10 ml of water is added. The solid is filtered off and crystallized from absolute ethanol to yield 12.3 g of the title compound, melting point 289°-291° C.

Workup

  1. temperatureis refluxed for 15 minutes during which time a precipitate
  2. customis formed
  3. temperatureThe mixture is cooled
  4. filtrationThe solid is filtered off
  5. customcrystallized from absolute ethanol

Sources & evidence

ORD record
ord-25427eb0ad0246bd9e516e0820cbe1ce
Source dataset
uspto-grants-1977_02
Patent number
US04006137

Reaction notes

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