Thionyl Chloride → HCID 12232349, compound

HRID 435640Notes

Reaction equation

HRID 435640 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:7]([S:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:8][CH:9]=1)[CH2:5]O.S(Cl)([Cl:19])=O>C1C=CC=CC=1>[F:1][C:2]1[CH:3]=[C:4]([C:7]([S:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:8][CH:9]=1)[CH2:5][Cl:19]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 122323463-Fluoro-6-(phenylthio)-benzyl alcohol

Product 1

HCID 12232349HCID 12232349, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

129 g of 3-fluoro-6-(phenylthio)-benzyl alcohol are dissolved in 385 ml of benzene and heated under reflux. 73 ml of thionyl chloride are added thereto and the resulting mixture is boiled for a further 30 minutes. The mixture is evaporated under reduced pressure. There is obtained 3-fluoro-6-(phenylthio)-benzyl chloride as a red-brown oil.

Workup

  1. temperatureheated
  2. temperatureunder reflux
  3. customThe mixture is evaporated under reduced pressure

Sources & evidence

ORD record
ord-db80e4db199b480a97512429479f9c64
Source dataset
uspto-grants-1977_02
Patent number
US04006145

Reaction notes

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