反应详情

The same operation as in Example (91d) was performed using ethyl 4-(7-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}-2,3-dihydro-4H-1,4-benzoxazin-4-yl)-4-oxobutanoate obtained in Example (95d) (45 mg, 0.10 mmol), 2 N lithium hydroxide (3 mL, 6 mmol) and methanol (5 mL), to obtain 10.4 mg of the title compound as a colorless solid (25%).