反应详情

温度

40 °C

Benzene sulfinic acid sodium salt, 49.2 g. (0.3 mole) was combined with 400 ml. of dimethyl formamide in a 1 liter flask. The mixture was stirred at 40° C. Chloroacetonitrile, 22.5 g. (0.3 mole) was added over a period of 5 minutes. The resulting mixture was stirred and heated at 40°-45° C. for 2 hours. The reaction mass was then poured into 600 ml. of water, and the solid insoluble product was collected by suction filtration and dried. There was obtained a yield of 29.8 g. of the title compound, m.p. 111°-112° C.

1. addition(0.3 mole) was added over a period of 5 minutes
2. stirringThe resulting mixture was stirred
3. temperatureheated at 40°-45° C. for 2 hours
4. additionThe reaction mass was then poured into 600 ml
5. filtrationof water, and the solid insoluble product was collected by suction filtration
6. customdried
7. customThere was obtained a yield of 29.8 g