反应详情

A 0.6 g. portion of 1,2,4-triazole-3-carboxamide is added to 5.4 ml. of a solution of 1N sodium methoxide in methanol contained in a test tube at room temperature. The mixture is shaken vigorously. Within about 1/2 to one minute most of the solid dissolves. The mixture is quickly filtered through a sintered glass funnel with vacuum. The light yellow filtrate is allowed to stand and deposits a colorless solid. A portion of methanol is added and the solid is collected, washed with methanol and air dried for one hour yielding 0.3 g. of product.

1. dissolutionWithin about 1/2 to one minute most of the solid dissolves
2. filtrationThe mixture is quickly filtered through a sintered glass funnel with vacuum
3. additionA portion of methanol is added
4. customthe solid is collected
5. washwashed with methanol and air
6. customdried for one hour
7. customyielding 0.3 g