Hydrochloric Acid → HCID 15606368, compound

Participants

Reaction Steps

Into a mixture of 87 gm of isobutyric acid amide and 82 gm of phosphorous acid, hydrogen chloride gas was introduced for 8 hours. During this time the mixture was stirred and the temperature was held at 155° -160° C. By further processing of the reaction mixture analogously to Example 1, the 1-amino-2-methylpropane-1,1 -diphosphonic acid was isolated and purified. The yield was 8 gm.

Provenance & Evidence