Diethyl Malonate → HCID 54711102, compound

HRID 435824Notes

Reaction equation

[NH2:1][C:2]1[CH2:7][CH2:6][CH:5]([CH3:8])[CH2:4][C:3]=1[C:9]([O:11]CC)=O.[C:14](OCC)(=[O:21])[CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17]>>[C:16]([C:15]1[C:14](=[O:21])[NH:1][C:2]2[CH2:7][CH2:6][CH:5]([CH3:8])[CH2:4][C:3]=2[C:9]=1[OH:11])([O:18][CH2:19][CH3:20])=[O:17]

Participants

Reactant 2

HCID 7761Diethyl Malonate

HCID 2142834656661-93-9

Product 1

HCID 54711102HCID 54711102, compound

Procedure

Condensation of ethyl 2-amino-5-methyl-cyclohex-1-ene-1-carboxylate (37 g; 0.202 mole) with diethyl malonate (32.4 g; 0.202 mole) at 110° C as described in Example 1 gave the title compound; m.p. (EtOH) 214°-216° C.

Sources & evidence

ORD record: ord-e09d1bd594104067bfb6b69505262870
Source dataset: uspto-grants-1977_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04006237

Reaction notes

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